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中文人类
GRPR - Gastrin Releasing Peptide Receptor
Alias:
BB2
BB2R
BRS2
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胃泌素释放肽(GRP)调节胃肠道和中枢神经系统的许多功能，包括胃肠道激素的释放、平滑肌细胞的收缩和上皮细胞的增殖，并且是对肿瘤组织具有强效刺激作用的生长因子。GRP的作用是通过胃泌素释放肽受体介导的。这个受体是一个糖基化的、7-跨膜的G蛋白偶联受体，它激活磷脂酶C信号通路。该受体在许多癌症中异常表达，如肺癌、结肠癌和前列腺癌。一位患有自闭症和多发性外生骨的患者被发现具有在染色体8和位于胃泌素释放肽受体基因内的染色体X断裂点之间的平衡易位。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GRPR Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
