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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Lrp2 - LDL receptor related protein 2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种蛋白质,具有多种功能,包括与PDZ结构域结合、胰岛素样生长因子I结合以及低密度脂蛋白颗粒受体结合活性。该蛋白参与多种过程,如细胞内血红蛋白的内吞导入、对维生素D的反应以及调控运输。该蛋白位于细胞的几种成分中,包括顶浆膜、轴突生长锥和刷状缘膜。它是受体复合物的一部分,用于研究高血压。它是常染色体显性多囊肾病的生物标志物,也是终末期肾病的、膜性肾小球肾炎和肾病的生物标志物。这个基因的人类同源物与Donnai-Barrow综合征和自身免疫性甲状腺炎有关。该基因与人类LRP2(低密度脂蛋白受体相关蛋白2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:29216
ENSEMBL:ENSRNOG00000056184
UNIPROT:P98158
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
29216
2
79
157465 bp
519.28
11
25
Lrp2 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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