Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
GRM7 - Glutamate Metabotropic Receptor 7
Alias:
GLUR7
MGLU7
GPRC1G
MGLUR7
NEDSHBA
PPP1R87
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
L-谷氨酸是中枢神经系统中的主要兴奋性神经递质,它可以激活离子型和代谢型谷氨酸受体。谷氨酸能神经传导涉及正常大脑功能的大部分方面,并在许多神经病理学状况中受到干扰。代谢型谷氨酸受体是一类G蛋白偶联受体,根据序列同源性、推测的信号传导机制和药理学特性分为三组。I组包括GRM1和GRM5,这些受体已被证明可以激活磷脂酶C。II组包括GRM2和GRM3,而III组包括GRM4、GRM6、GRM7和GRM8。II组和III组受体与环腺苷酸级联的抑制有关,但它们的激动剂选择性不同。已发现此基因的多重转录变异体,编码不同的异构体。[RefSeq,2009年6月提供]
Related ID:
NCBI:2917
ENSEMBL:ENSG00000196277
HGNC:4599
UNIPROT:Q14831
OMIM:604101
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2917
6
10
880419 bp
102.25
186
4
12
11
GRM7 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top