Nedd4l - NEDD4 like E3 ubiquitin protein ligase

Enables potassium channel inhibitor activity and ubiquitin-protein transferase activity. Involved in several processes, including positive regulation of caveolin-mediated endocytosis; protein monoubiquitination; and ventricular cardiac muscle cell action potential. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Apr 2022]