Log In|Sign Up
中文人类
PYCARD - PYD And CARD Domain Containing
Alias:
ASC
TMS
TMS1
CARD5
TMS-1
Favorite
这个基因编码一个由两个蛋白质相互作用结构域组成的衔接蛋白：一个N端的PYRIN-PAAD-DAPIN结构域（PYD）和一个C端的caspase招募结构域（CARD）。PYD和CARD结构域是六股螺旋死亡结构域折叠超家族的成员，通过激活caspase在炎症和凋亡信号通路中调节大型信号复合体的组装。在正常细胞中，这种蛋白位于细胞质中；然而，在经历凋亡的细胞中，它会在核周附近形成球状聚集物。已发现这个基因的两个转录变异体编码不同的异构体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PYCARD Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
