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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Mtrr - 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Alias:
MSR
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活NADPH-血红蛋白还原酶活性;甲硫氨酸合成酶还原酶活性;以及核苷酸结合活性。参与几个过程,包括S-腺苷甲硫氨酸循环;羧酸代谢过程;以及胱硫醚β-合成酶活性的负调控。位于中间纤维细胞骨架和核质中。在细胞质中活性。该基因的人类同源物涉及几种疾病,包括内分泌腺癌(多种);心脏病(多种);血液癌症(多种);同型胱氨酸尿症;以及同型胱氨酸尿症-巨幼红细胞贫血cblE型。与人类MTRR(5-甲基四氢叶酸-同型半胱氨酸甲基转移酶还原酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:290947
ENSEMBL:ENSRNOG00000017826
UNIPROT:Q498R1
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
290947
11
13
32435 bp
78.03
5
1
Mtrr Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
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References Literature
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IF
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