Ash2l - ASH2 like histone lysine methyltransferase complex subunit

Predicted to enable beta-catenin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to histone methyltransferase activity (H3-K4 specific). Predicted to be involved in histone H3-K4 methylation; positive regulation of cell population proliferation; and response to estrogen. Predicted to act upstream of or within cellular response to DNA damage stimulus and positive regulation of transcription by RNA polymerase II. Predicted to be located in euchromatin and nucleus. Predicted to be part of MLL1 complex; MLL3/4 complex; and Set1C/COMPASS complex. Biomarker of schizophrenia. Orthologous to human ASH2L (ASH2 like, histone lysine methyltransferase complex subunit). [provided by Alliance of Genome Resources, Apr 2022]