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中文人类
GRIN2A - Glutamate Ionotropic Receptor NMDA Type Subunit 2A
Alias:
LKS
EPND
FESD
NR2A
GluN2A
NMDAR2A
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这个基因编码谷氨酸门控离子通道蛋白家族的成员。编码的蛋白质是N-甲基-D-天门冬氨酸(NMDA)受体亚基。NMDA受体既是配体门控又是电压依赖的，参与长期增强，这是一种活动依赖的突触传递效率增加，被认为与某些类型的记忆和学习有关。这些受体对钙离子通透，激活导致钙流入后突触细胞，从而导致几个信号级联的激活。这个基因的破坏与局灶性癫痫和伴有或不伴有认知障碍的语言障碍相关。可选的剪接导致多个转录变异体。[由RefSeq提供，2014年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GRIN2A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
