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中文人类
GRIN1 - Glutamate Ionotropic Receptor NMDA Type Subunit 1
Alias:
NR1
MRD8
GluN1
NMDA1
DEE101
NDHMSD
NDHMSR
NMD-R1
NMDAR1
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这个基因编码的蛋白质是N-甲基-D-天冬氨酸受体的关键亚基，该受体属于谷氨酸受体通道超家族，是一个具有多个亚基的异质性蛋白质复合体，用于形成配体门控离子通道。这些亚基在突触的可塑性中起着关键作用，被认为与记忆和学习有关。细胞特异性因子被认为可以控制不同异构体的表达，这可能有助于亚基的功能多样性。已经描述了可替代剪接的转录变异体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GRIN1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
