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中文人类
GRIK3 - Glutamate Ionotropic Receptor Kainate Type Subunit 3
Alias:
EAA5
GLR7
GLUR7
GluK3
GluR7a
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谷氨酸受体是哺乳动物大脑中占主导地位的兴奋性神经递质受体，在多种正常的神经生理过程中被激活。该基因产物属于谷氨酸受体的卡内酸家族，由四个亚单位组成，作为配体激活的离子通道。目前尚不确定该基因编码的亚单位是否受RNA编辑的影响，因为该家族的其他两个成员（GRIK1和GRIK2）也是如此。一个Ser310Ala多态性与精神分裂症有关，但关于其与酒精中毒性震颤谵妄的发病机制的关联的报告相互矛盾。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GRIK3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
