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中文人类
GRIK2 - Glutamate Ionotropic Receptor Kainate Type Subunit 2
Alias:
EAA4
GLR6
MRT6
GLUK6
GLUR6
GluK2
NEDLAS
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谷氨酸受体是哺乳动物大脑中主要的兴奋性神经递质受体，在各种正常的神经生理过程中被激活。这个基因产物属于谷氨酸受体的高钾家族，由四个亚单位组成，作为配体激活的离子通道发挥作用。这个基因编码的亚单位在第一和第二跨膜结构域内的多个位点受到RNA编辑的影响，被认为会改变受体复合物的结构和功能。这个基因的突变与常染色体隐性认知障碍有关。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GRIK2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
