人类

DCPS - Decapping Enzyme, Scavenger

Alias:
ARS
DCS1
HSL1
HINT5
HINT-5
HSPC015
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码组氨酸三家族的一员,该家族是去除含有5' mRNA帽结构的短mRNA片段的焦磷酸酶,这些片段出现在3' - 5' mRNA降解途径中,跟随去腺苷化和外切体介导的周转。这种酶水解帽结构(7-甲基鸟苷核苷三磷酸)的三磷酸键,产生7-甲基鸟苷一磷酸和核苷二磷酸。它保护细胞免受这些短、有帽的mRNA片段的潜在有毒积累,并调节其他帽结合蛋白的活性,这些蛋白受到其积累的抑制。它还可以作为预-mRNA剪接和microRNA周转的转录特异性调节物。[由RefSeq,2017年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
6
45946 bp
38.61
62
2
5
25

DCPS Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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