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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DCPS - Decapping Enzyme, Scavenger
Alias:
ARS
DCS1
HSL1
HINT5
HINT-5
HSPC015
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码组氨酸三家族的一员,该家族是去除含有5' mRNA帽结构的短mRNA片段的焦磷酸酶,这些片段出现在3' - 5' mRNA降解途径中,跟随去腺苷化和外切体介导的周转。这种酶水解帽结构(7-甲基鸟苷核苷三磷酸)的三磷酸键,产生7-甲基鸟苷一磷酸和核苷二磷酸。它保护细胞免受这些短、有帽的mRNA片段的潜在有毒积累,并调节其他帽结合蛋白的活性,这些蛋白受到其积累的抑制。它还可以作为预-mRNA剪接和microRNA周转的转录特异性调节物。[由RefSeq,2017年4月提供]
Related ID:
NCBI:28960
ENSEMBL:ENSG00000110063
HGNC:29812
UNIPROT:Q96C86
OMIM:610534
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
28960
2
6
45946 bp
38.61
62
2
5
25
DCPS Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
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Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Alphabetical
Cell-specific RNA expression
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Regulation
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Type
Name
MGI
Strain of Origin
Publications
Mutations
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Related Drugs
Name
CAS Number
Status
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Link
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References Literature
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