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中文大鼠
Nit1 - nitrilase 1
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这个基因编码的蛋白质是腈水解酶超家族的一员。腈水解酶是非肽C-N水解酶。在哺乳动物中，腈水解酶形成小分子C-N键，如酸酰胺、氨基甲酸酯和脲。Nit1缺陷小鼠表现出表型，包括细胞增殖增加、对DNA损伤的抵抗力增加，以及N-亚硝基甲基苯丙胺诱导的小鼠前胃肿瘤数量的增加，提示其具有肿瘤抑制功能。可变剪接导致多个转录变异体。[RefSeq,2015年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Nit1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
