人类

GRIA3 - Glutamate Ionotropic Receptor AMPA Type Subunit 3

Alias:
GLUR3
GLURC
GluA3
MRX94
MRXSW
GLUR-C
iGluR3
GLUR-K3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
谷氨酸受体是哺乳动物大脑中主要的兴奋性神经递质受体,在各种正常的神经生理过程中被激活。这些受体是由多个亚基组成的异源蛋白复合物,这些亚基被安排形成配体门控离子通道。谷氨酸受体的分类是基于它们不同药理学激动剂的激活。这个基因编码的亚基属于一个AMPA(α-氨基-3-羟基-5-甲基-4-异唑丙酸)敏感谷氨酸受体家族,并且受到RNA编辑的影响(AGA->GGA;R->G)。在这个位置上的选择性剪接产生了不同的异构体,它们的信号传导特性可能不同。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
16
306638 bp
101.16
380
2
12
8

GRIA3 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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