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中文人类
GRB2 - Growth Factor Receptor Bound Protein 2
Alias:
ASH
Grb3-3
MST084
NCKAP2
MSTP084
EGFRBP-GRB2
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这个基因编码的蛋白质与表皮生长因子受体结合，包含一个SH2结构域和两个SH3结构域。其两个SH3结构域能引导与其他蛋白质的富脯氨酸区域形成复合物，其SH2结构域能结合酪氨酸磷酸化序列。这个基因与线虫的Sem5基因相似，参与信号转导途径。已发现这个基因有两个可变剪接的转录变异体，编码不同的异构体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GRB2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
