Predicted to enable serine-type endopeptidase activity. Involved in neuron differentiation and response to nutrient levels. Located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; coronary artery disease; hyperinsulinism; myopia; and type 2 diabetes mellitus. Orthologous to human PARL (presenilin associated rhomboid like). [provided by Alliance of Genome Resources, Apr 2022]