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Nlrp3 - NLR family, pyrin domain containing 3

Alias:
Cias1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有预测的DNA结合转录因子结合活性;具有相同的蛋白质结合活性;以及序列特异性的DNA结合活性。参与白细胞迁移,涉及炎症反应;对乙醇的反应;以及对有机环状化合物的反应。预测位于高尔基膜和细胞核中。预测是NLRP3炎症小体复合物的一部分。是酒精性肝炎的生物标志物。该基因的人类同源物与CINCA综合征、Muckle-Wells综合征、常染色体显性非综合征性耳聋34、家族性冷炎症状态1和荨麻疹有关。与人类NLRP3(NLR家族含吡喃域3)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
8
9
27045 bp
118.54
38
1

Nlrp3 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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