Lgr4 - leucine-rich repeat-containing G protein-coupled receptor 4

Predicted to enable Roundabout binding activity; heparin binding activity; and transmembrane signaling receptor activity. Predicted to be involved in several processes, including metanephros development; regulation of gene expression; and regulation of signal transduction. Predicted to act upstream of or within several processes, including epithelial cell proliferation involved in renal tubule morphogenesis; intestinal stem cell homeostasis; and male genitalia development. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to human LGR4 (leucine rich repeat containing G protein-coupled receptor 4). [provided by Alliance of Genome Resources, Apr 2022]