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中文人类
ANGPT2 - Angiopoietin 2
Alias:
ANG2
AGPT2
LMPHM10
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这个基因属于血管生成素家族的生长因子。这个基因编码的蛋白质是血管生成素1的拮抗剂，而血管生成素1和血管生成素2都是内皮TEK受体酪氨酸激酶的配体。血管生成素2在多种炎症性疾病中上调，并与直接控制炎症相关信号通路有关。编码的蛋白质影响胚胎发育和肿瘤发生过程中的血管生成，破坏血管生成素1的血管重塑能力，并可能诱导内皮细胞凋亡。这个基因是急性呼吸窘迫综合症的预后生物标志物。[RefSeq，2020年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ANGPT2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
