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中文人类
RSPO1 - R-spondin 1
Alias:
RSPO
CRISTIN3
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这个基因编码了一个有两个富含半胱氨酸的类似furin的域和一个thrombospondin类型1域的分泌激活蛋白。编码的蛋白质是富含亮氨酸重复的G蛋白偶联受体（LGR蛋白）的配体，并且正向调节Wnt信号通路。在小鼠中，该蛋白质诱导了隐窝细胞增殖的快速发生并增加了肠道上皮愈合，提供了对化疗引起的不良影响的保护作用。替代剪接导致了多个转录变体。[由RefSeq提供，2014年4月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RSPO1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
