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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CES4A - Carboxylesterase 4A
Alias:
CES6
CES8
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码羧酸酯酶大家族的一员。这个家族的成员负责水解或转移各种外源性物质,如可卡因和海洛因,以及具有酯、硫酯或酰胺键的内源性底物。它们还参与脂肪酸和胆固醇酯的代谢,可能参与血脑屏障系统。这个基因,也被称为CES6,编码一种分泌酶,可能参与神经组织和其他身体组织和脑脊液中药物和外来物质的解毒。已经报道了许多编码不同异型体的转录变异体,但一些变异体的完整性质和/或生物学有效性尚未确定。[由RefSeq,2010年6月提供]
Related ID:
NCBI:283848
ENSEMBL:ENSG00000172824
HGNC:26741
UNIPROT:Q5XG92
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
283848
20
14
21829 bp
63.53
24
--
4
4
CES4A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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