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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CDH20 - Cadherin 20
Alias:
Cdh7
CDH7L3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是cadherin超家族中的一类II型经典钙粘蛋白,是位于染色体18上一个簇中的三个钙粘蛋白7样基因之一。编码的膜蛋白是一种依赖于钙的细胞间粘附糖蛋白,由五个细胞外的钙粘蛋白重复序列、一个跨膜区和一个高度保守的细胞质尾组成。II型(非典型)钙粘蛋白是根据它们缺乏I型钙粘蛋白的HAV细胞粘附识别序列而定义的。由于细胞内粘附的干扰是肿瘤细胞侵袭和转移的前提,因此钙粘蛋白被认为是肿瘤抑制基因的候选基因。[由RefSeq,2008年7月提供]
Related ID:
NCBI:28316
ENSEMBL:ENSG00000101542
HGNC:1760
UNIPROT:Q9HBT6
OMIM:605807
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
28316
2
12
222350 bp
88.99
26
--
3
4
CDH20 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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