人类

CCR10 - C-C Motif Chemokine Receptor 10

Alias:
GPR2
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
小分子化学诱引物是一组小型(约8至14kD),主要碱性,结构上相关的分子,通过与其7-跨膜G蛋白偶联受体子集相互作用,调节各种类型白细胞的活动。化学诱引物在免疫系统的发育、稳态和功能中也起着基本作用,并对中枢神经系统细胞以及参与血管生成的内皮细胞产生影响。化学诱引物分为两大亚家族,即CXC和CC,根据第一个2个保守半胱氨酸残基的排列进行分类;在CXC化学诱引物中,两个半胱氨酸由一个氨基酸隔开,而在CC化学诱引物中则相邻。CCR10是CCL27(SCYA27;MIM 604833)的受体;CCR10-CCL27相互作用涉及T细胞介导的皮肤炎症(Homey等,2002[PubMed 11821900])。[由OMIM于2008年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
2
2955 bp
38.42
17
--
5
6

CCR10 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top