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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
GOT2 - Glutamic-oxaloacetic Transaminase 2
Alias:
KAT4
DEE82
KATIV
KYAT4
mitAAT
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
谷氨酸-草酰乙酸转氨酶是一种依赖于吡哆醇磷酸酶的酶,存在于细胞质和线粒体内膜中,分别是GOT1和GOT2形式。GOT在氨基酸代谢和尿素和三羧酸循环中发挥作用。这两种酶是同源二聚体,显示出高度的相似性。已发现此基因的两个转录变异体编码不同的异构体。[RefSeq,2013年10月提供]
Related ID:
NCBI:2806
ENSEMBL:ENSG00000125166
HGNC:4433
UNIPROT:P00505
OMIM:138150
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2806
2
10
27186 bp
47.52
94
1
9
13
GOT2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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