Predicted to enable identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in proteasomal protein catabolic process. Acts upstream of or within several processes, including inner cell mass cell proliferation; positive regulation of astrocyte differentiation; and positive regulation of mRNA splicing, via spliceosome. Located in cytoplasm; lipid droplet; and nucleus. Is expressed in several structures, including extraembryonic component and genitourinary system. Orthologous to human PRPF19 (pre-mRNA processing factor 19). [provided by Alliance of Genome Resources, Apr 2022]