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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Vkorc1 - vitamin K epoxide reductase complex, subunit 1
Alias:
D7Wsu86e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
维生素K对凝血是必不可少的,但必须经过酶促活化。这种酶促活化的维生素K形式是一种还原形式,用于一些凝血蛋白质中的谷氨酸残基的羧化。这个基因的产品编码负责将维生素K 2,3-环氧化物还原为酶促活化形式的酶。维生素K缺乏和抗维生素K药物华法林都可能导致致命性出血,而这个基因的产品对华法林是敏感的。在人类中,这个基因的突变可能与维生素K依赖性凝血因子缺乏有关,在人类和大鼠中,可能与华法林抗性有关。[由RefSeq,2008年7月提供]
Related ID:
NCBI:27973
ENSEMBL:ENSMUSG00000096145
UNIPROT:Q9CRC0
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
27973
2
3
2599 bp
17.77
7
5
Vkorc1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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