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中文人类
HTRA2 - HtrA Serine Peptidase 2
Alias:
OMI
MGCA8
PARK13
PRSS25
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这个基因编码丝氨酸蛋白酶。该蛋白质定位在内质网并与有丝分裂激活蛋白激酶14的可变剪接形式相互作用。该蛋白质也定位在线粒体上，在凋亡刺激后释放到细胞质中。该蛋白质被认为通过结合凋亡抑制蛋白含杆状病毒IAP重复序列的4来诱导凋亡。这个蛋白质的核定位也被观察到。这个基因的可变剪接导致多个转录变异体编码不同的异构体。[RefSeq,2016年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HTRA2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
