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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Abcg5 - ATP binding cassette subfamily G member 5
Alias:
cmp
trac
sterolin-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是ATP结合盒(ABC)转运蛋白超家族的一员。ABC蛋白在细胞内外膜之间运输各种分子。ABC基因分为七个不同的亚家族(ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White)。这个蛋白质是White亚家族的一员,作为半转运蛋白限制肠道对固醇的吸收并促进其胆汁排泄。小鼠中这个基因的破坏导致血小板减少、出血时间延长、贫血、白细胞减少、不育、寿命缩短和心肌病。缺乏这个基因的小鼠表现出坐固醇血症的症状。[RefSeq,2015年11月提供]
Related ID:
NCBI:27409
ENSEMBL:ENSMUSG00000040505
UNIPROT:Q99PE8
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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Reference
27409
1
13
24838 bp
73.24
5
19
Abcg5 Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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