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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Abca7 - ATP-binding cassette, sub-family A (ABC1), member 7
Alias:
ABCX
Abc51
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是ATP结合盒(ABC)转运蛋白超家族的一员。ABC蛋白在细胞内外膜之间运输各种分子。ABC基因分为七个不同的亚家族(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)。这个蛋白质是ABC1亚家族的一员。ABC1亚家族的成员是仅存在于多细胞真核生物中的主要ABC亚家族。这个蛋白质广泛表达,在脾和造血组织中表达最高。这个基因的缺陷导致阿尔茨海默病小鼠模型中淀粉样蛋白-β沉积增加,认为相关的人类蛋白质在免疫系统的细胞中参与脂质稳态。[由RefSeq,2017年1月提供]
Related ID:
NCBI:27403
ENSEMBL:ENSMUSG00000035722
UNIPROT:Q91V24
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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27403
3
47
19079 bp
236.88
10
14
Abca7 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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