Skp2 - S-phase kinase-associated protein 2

Predicted to enable identical protein binding activity. Acts upstream of or within several processes, including cellular protein metabolic process; mitotic cell cycle phase transition; and positive regulation of intracellular estrogen receptor signaling pathway. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including blastocyst; compacted morula; and retina nuclear layer. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human SKP2 (S-phase kinase associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]