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中文人类
GCLC - Glutamate-cysteine Ligase Catalytic Subunit
Alias:
GCL
GCS
GLCL
GLCLC
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谷氨酸-半胱氨酸连接酶，也称为γ-谷氨酰半胱氨酸合成酶，是谷胱甘肽合成的第一限速酶。该酶由两个亚基组成，一个重催化亚基和一个轻调控亚基。这个基因座编码催化亚基，而调控亚基来自位于染色体1p22-p21上的不同基因。这个基因座的突变与由于γ-谷氨酰半胱氨酸合成酶缺陷而导致的溶血性贫血以及心肌梗死易感性有关。[RefSeq，2010年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GCLC Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
