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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pla2g7 - phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Alias:
PAF-AH
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活1-烷基-2-乙酰甘油磷酸胆碱酯酶活性;钙依赖性磷脂酶A2活性;和磷脂类结合活性。预测参与几个过程,包括甘油磷脂分解过程;血浆脂蛋白颗粒重塑;和单核细胞趋化作用的正向调节。预测在炎症反应的上游或内部发挥作用。预测位于细胞质和细胞外空间。预测是高密度脂蛋白颗粒和低密度脂蛋白颗粒的一部分。在几个结构中表达,包括消化系统;中枢神经系统;生殖泌尿系统;皮肤和感觉器官。这个基因的人类同源物与几种疾病有关,包括动脉疾病(多种);肾小球肾炎(多种);溶血性尿毒症综合征;蛋白尿(多种);和2型糖尿病。与人类PLA2G7(磷脂酶A2组VII)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:27226
ENSEMBL:ENSMUSG00000023913
UNIPROT:Q60963
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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Reference
27226
4
12
44209 bp
49.26
6
7
Pla2g7 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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