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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Trp53bp1 - transformation related protein 53 binding protein 1
Alias:
53BP1
m53BP1
p53BP1
Tp53bp1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
修复损伤的DNA结合活性;甲基化组蛋白结合活性;端粒DNA结合活性。参与非同源末端连接的双链断裂修复;负调控同源重组的双链断裂修复;以及同型转换的正调控。在DNA修复的上游或内部发挥作用。位于染色体和核体。DNA修复复合物的一部分。在肠系膜、肺、肾单位、神经系统和感觉器官中表达。与人类的TP53BP1(肿瘤蛋白p53结合蛋白1)正同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:27223
ENSEMBL:ENSMUSG00000043909
UNIPROT:P70399
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
27223
21
28
101515 bp
212.74
15
26
Trp53bp1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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