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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
C5AR2 - Complement C5a Receptor 2
Alias:
C5L2
GPF77
GPR77
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个G-蛋白偶联受体1家族成员,参与先天免疫反应的补体系统。与经典的G-蛋白偶联受体不同,编码的蛋白质不与其他细胞内的G-蛋白结合。它可能通过β-arrestin途径调节信号传导,或者作为诱饵受体发挥作用。这个基因可能参与冠状动脉硬化和脓毒病病理学。可变剪接产生多个转录子变异体。[RefSeq,2012年11月提供]
Related ID:
NCBI:27202
ENSEMBL:ENSG00000134830
HGNC:4527
UNIPROT:Q9P296
OMIM:609949
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
27202
3
2
15155 bp
36.08
40
--
8
11
C5AR2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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