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中文人类
GPC3 - Glypican 3
Alias:
SGB
DGSX
MXR7
SDYS
SGBS
OCI-5
SGBS1
GTR2-2
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细胞表面的肝素硫酸糖蛋白聚糖是由一个膜相关蛋白质核心和可变数量的肝素硫酸酯链组成的。糖蛋白相关整膜蛋白聚糖家族（GRIPS）的成员包含一个通过糖基磷酯酰肌醇连接锚定到细胞质膜的核心蛋白质。这些蛋白质可能参与细胞分裂和生长调节的控制。这个基因编码的蛋白质可以结合并抑制CD26的二肽肽酶活性，并在某些细胞类型中诱导凋亡。这个基因的缺失突变与Simpson-Golabi-Behmel综合征（也称为Simpson畸形综合征）有关。可变剪接导致多个转录变异体。[RefSeq, 2009年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GPC3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
