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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IL37 - Interleukin 37
Alias:
FIL1
FIL1Z
IL-1H
IL-23
IL-37
IL1F7
IL1H4
IL-1F7
IL-1H4
IL1RP1
IL-1RP1
FIL1(ZETA)
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白介素1细胞因子家族的成员。这种细胞因子可以结合,可能是白介素18受体(IL18R1/IL-1Rrp)的配体。这种细胞因子还结合白介素18结合蛋白(IL18BP),这是一种白介素18(IL18)的抑制性结合蛋白,随后与IL18受体β亚基形成复合物,通过该复合物抑制IL18的活性。这个基因以及另外八个白介素1家族基因在2号染色体上形成一个细胞因子基因簇。已报告了五种可变剪接转录变体,编码不同的等位基因。[由RefSeq提供,2008年7月]
Related ID:
NCBI:27178
ENSEMBL:ENSG00000125571
HGNC:15563
UNIPROT:Q9NZH6
OMIM:605510
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Related Mouse Models
Reference
27178
5
6
7718 bp
24.13
10
2
--
11
IL37 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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