人类

IL37 - Interleukin 37

Alias:
FIL1
FIL1Z
IL-1H
IL-23
IL-37
IL1F7
IL1H4
IL-1F7
IL-1H4
IL1RP1
IL-1RP1
FIL1(ZETA)
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白介素1细胞因子家族的成员。这种细胞因子可以结合,可能是白介素18受体(IL18R1/IL-1Rrp)的配体。这种细胞因子还结合白介素18结合蛋白(IL18BP),这是一种白介素18(IL18)的抑制性结合蛋白,随后与IL18受体β亚基形成复合物,通过该复合物抑制IL18的活性。这个基因以及另外八个白介素1家族基因在2号染色体上形成一个细胞因子基因簇。已报告了五种可变剪接转录变体,编码不同的等位基因。[由RefSeq提供,2008年7月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
6
7718 bp
24.13
10
2
--
11

IL37 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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