人类

CYTH4 - Cytohesin 4

Alias:
CYT4
PSCD4
DJ63G5.1
cytohesin-4
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码PSCDA家族蛋白质的一员,该家族蛋白质具有N端螺旋卷结构,中央Sec7结构域和C端pleckstrin同源性(PH)结构域。螺旋卷结构参与同源二聚化,Sec7结构域含有鸟苷酸交换蛋白(GEP)活性,PH结构域与磷脂相互作用,并负责PSCDA与膜的结合。这个家族的成员作为ADP-核糖基化因子(ARFs)的GEP发挥作用,ARFs是参与囊泡转运途径的鸟苷酸结合蛋白。这个蛋白在体外展示了与ARF1和ARF5的GEP活性,但与ARF6无活性。已经发现这个基因的替代剪接转录变异体。[RefSeq,2015年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
13
32834 bp
45.67
21
--
3
5

CYTH4 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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