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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Adamts16 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于“去整合素和金属蛋白酶含血栓素主题模式”(ADAMTS)家族的多结构域基质相关金属内肽酶,这些酶在组织形态发生和病理生理重塑、炎症和血管生物学中具有多种作用。这个基因与Wilms瘤蛋白Wt1在胚胎肾发育中的肾小球中共表达。编码的前原原蛋白经历蛋白水解处理以产生活性酶。[RefSeq,2016年7月提供]
Related ID:
NCBI:271127
ENSEMBL:ENSMUSG00000049538
UNIPROT:Q69Z28
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
271127
12
23
114040 bp
136.28
6
2
Adamts16 Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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