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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Eif2ak4 - eukaryotic translation initiation factor 2 alpha kinase 4
Alias:
GCN2
MGCN2
2610011M03
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活真核翻译起始因子2alpha激酶活性和tRNA结合活性。参与几个过程,包括GCN2介导的信号传导;学习或记忆;以及翻译起始的调节。在细胞对饥饿的响应的上游或内部发挥作用;内质网未折叠蛋白响应;以及翻译的调节。是多聚体的一部分。在几个结构中表达,包括肠道;血淋巴系统腺体;肝脏;肺;和卵巢。这个基因的人类同源物与肺静脉闭塞性疾病有关。与人类EIF2AK4(真核翻译起始因子2alpha激酶4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:27103
ENSEMBL:ENSMUSG00000005102
UNIPROT:Q9QZ05
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
27103
8
39
86651 bp
186.49
4
24
Eif2ak4 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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