人类

FOXP1 - Forkhead Box P1

Alias:
MFH
QRF1
12CC4
hFKH1B
HSPC215
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因属于翼状螺杆转录因子家族(FOX)的P亚家族。翼状螺杆转录因子在发育和成年期在组织和细胞类型特异性的基因转录调控中扮演重要角色。翼状螺杆P1蛋白含有DNA结合结构域和蛋白质-蛋白质结合结构域。这个基因可能作为肿瘤抑制因子发挥作用,因为它在几种肿瘤类型中丢失,并且位于被认为包含一个或多个肿瘤抑制因子的染色体区域(3p14.1)。可变剪接导致多个转录本变异体,编码不同的异构体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
17
21
629271 bp
75.32
663
6
12
28

FOXP1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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