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中文人类
ABL2 - ABL Proto-oncogene 2, Non-receptor Tyrosine Kinase
Alias:
ARG
ABLL
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这个基因编码Abelson家族的非受体酪氨酸蛋白激酶成员。该蛋白质与c-abl癌基因1蛋白质高度相似，包括酪氨酸激酶、SH2和SH3结构域，并通过其C端F-肌动蛋白和微管结合序列在细胞骨架重排中发挥作用。这个基因在正常和肿瘤细胞中都有表达，并与ets变异体6基因在白血病中涉及易位。已经发现这个基因的多个可变剪接转录变异体编码不同的蛋白质异构体。[由RefSeq提供，2009年11月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ABL2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
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CAS Number
Status
Phase
Link
References Literature
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PMID
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Year
IF
