Slc4a11 - solute carrier family 4, sodium bicarbonate transporter-like, member 11

Predicted to enable ion transmembrane transporter activity; protein dimerization activity; and water transmembrane transporter activity. Involved in fluid transport; ion homeostasis; and regulation of mesenchymal stem cell differentiation. Located in basolateral plasma membrane. Is expressed in metanephros and vomeronasal organ. Used to study congenital hereditary endothelial dystrophy of cornea. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; congenital hereditary endothelial dystrophy of cornea; and corneal dystrophy-perceptive deafness syndrome. Orthologous to human SLC4A11 (solute carrier family 4 member 11). [provided by Alliance of Genome Resources, Apr 2022]