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Ern2 - endoplasmic reticulum (ER) to nucleus signalling 2

Alias:
Ern1
Ire1
Ire1b
mIre1
ire1-beta
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种预测功能,包括ATP结合活性;镁离子结合活性;以及未折叠蛋白质结合活性。参与多个过程,包括JUN激酶活性的正向调节;DNA模板的转录调节;以及内质网应激的反应。作为内质网应激反应中的内在凋亡信号通路的上游或内部。位于内质网质量控制系统。是IRE1-TRAF2-ASK1复合物的一部分。在中枢神经系统和视网膜中表达。与人类的ERN2(内质网到核信号2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
11
22
16339 bp
101.26
6
10

Ern2 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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