Dagla - diacylglycerol lipase, alpha

Enables hydrolase activity. Involved in G protein-coupled glutamate receptor signaling pathway; regulation of neuroinflammatory response; and retrograde trans-synaptic signaling by endocannabinoid. Acts upstream of or within several processes, including arachidonic acid metabolic process; endocannabinoid signaling pathway; and neurotransmitter biosynthetic process. Located in dendritic spine membrane; postsynaptic membrane; and varicosity. Is integral component of postsynaptic membrane. Is expressed in brain and olfactory epithelium. Orthologous to human DAGLA (diacylglycerol lipase alpha). [provided by Alliance of Genome Resources, Apr 2022]