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中文人类
GFRA2 - GDNF Family Receptor Alpha 2
Alias:
NTNRA
RETL2
TRNR2
GDNFRB
NRTNR-ALPHA
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胶质细胞系衍生神经营养因子（GDNF）和中枢神经营养素（NTN）是两种在结构上相关的强效神经营养因子，它们在神经元生存和分化的控制中扮演关键角色。这个基因编码的蛋白质是GDNF受体家族的成员。它是一种通过糖磷脂酰肌醇（GPI）连接在细胞表面的受体，既可以结合GDNF也可以结合NTN，并调节RET酪氨酸激酶受体的激活。与它的其他家族成员相比，这个基因优先作为NTN的受体发挥作用。这个基因是RET相关疾病的候选基因。已经发现这个基因有多种编码不同异型的转录变异体。[由RefSeq，2009年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GFRA2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
