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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
GCKR - Glucokinase Regulator
Alias:
GKRP
FGQTL5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个属于GCKR亚家族的蛋白质,该蛋白质属于SIS(糖异构酶)家族。这个基因产物是一个调节蛋白,通过非共价结合形成与酶的失活复合物来抑制肝和胰腺胰岛细胞中的葡萄糖激酶。这个基因被认为是青少年晚期发病型糖尿病(MODY)的一种易感基因候选物。[由RefSeq,2008年7月提供]
Related ID:
NCBI:2646
ENSEMBL:ENSG00000084734
HGNC:4196
UNIPROT:Q14397
OMIM:600842
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2646
4
19
26846 bp
68.69
140
1
9
12
GCKR Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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