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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mapk8 - mitogen-activated protein kinase 8
Alias:
JNK
JNK1
Prkm8
SAPK1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活JUN激酶活性和蛋白质丝氨酸/苏氨酸/酪氨酸激酶活性。参与几个过程,包括JNK级联;神经元的产生;以及细胞蛋白质代谢过程的正向调节。在几个过程的上游或内部发挥作用,包括细胞对一氧化氮的反应;背部身份的确定;以及蛋白质磷酸化。位于几个细胞组件中,包括基部树突;线粒体;和podosome。在几个结构中表达,包括中枢神经系统;生殖泌尿系统;口腔区域上皮;感觉器官;和皮肤。该基因的人类同源物涉及腹主动脉瘤;慢性皮肤念珠菌病;结肠直肠癌;直肠良性肿瘤;和2型糖尿病。与人类MAPK8(促生长蛋白激活的蛋白激酶8)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:26419
ENSEMBL:ENSMUSG00000021936
UNIPROT:Q91Y86
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
26419
8
12
69361 bp
44.23
9
30
Mapk8 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Type
Name
MGI
Strain of Origin
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No data available
References Literature
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IF
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