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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mapk10 - mitogen-activated protein kinase 10
Alias:
JNK3
Serk2
JNK3B1
JNK3B2
p493F12
p54bSAPK
SAPK(beta)
C230008H04Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是MAP激酶家族的成员。MAP激酶作为多个生物化学信号的整合点,参与多种细胞过程,如增殖、分化、转录调节和发育。这个激酶在神经系统的一组特定神经元中特异地表达,并通过苏氨酸和酪氨酸磷酸化激活。小鼠中这个基因的定向缺失提示它可能参与应激诱导的神经元凋亡。已经发现这个基因有不同的剪接转录变异体,编码不同的异构体。最近的研究提供了这个基因中翻译读穿的证据,并通过使用一个替代的帧内翻译终止密码子表达了额外的C-末端延伸的异构体。[RefSeq,2017年12月提供]
Related ID:
NCBI:26414
ENSEMBL:ENSMUSG00000046709
UNIPROT:Q61831
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
26414
25
15
302788 bp
52.53
6
18
Mapk10 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
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References Literature
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IF
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