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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mapk1 - mitogen-activated protein kinase 1
Alias:
ERK
Erk2
MAPK2
PRKM2
Prkm1
p41mapk
p42mapk
9030612K14Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个具有多种功能的蛋白质,包括与相同蛋白质结合活性,磷酸酪氨酸残基结合活性,以及蛋白激酶活性。它参与肽基-丝氨酸磷酸化,肽基-苏氨酸磷酸化,以及对尼古丁的反应。该基因在几个过程中起到上游或内部作用,包括动物器官发育,细胞表面受体信号通路,以及细胞对细胞因子刺激的响应。它位于几个细胞成分中,包括胞质,线粒体和伪足。它在几个结构中表达,包括消化系统,早期胎囊,泌尿系统,神经系统和感觉器官。它用于研究Weissenbacher-Zweymuller综合征,自闭症谱系障碍和velocardiofacial综合征。这个基因的人类同源物与Noonan综合征13,腺癌(多种),肺高血压和肾细胞癌有关。它与人类的MAPK1(促生长因子激活的蛋白激酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:26413
ENSEMBL:ENSMUSG00000063358
UNIPROT:P63085
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
26413
3
9
64072 bp
41.28
16
27
Mapk1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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