人类

GCG - Glucagon

Alias:
GLP1
GLP2
GRPP
GLP-1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质实际上是一个前原蛋白,它被切割成四个不同的成熟肽。其中一种,胰高血糖素,是一种胰腺激素,通过刺激肝糖原分解和葡萄糖生成来对抗胰岛素的降低血糖作用。胰高血糖素是特异性G蛋白连接受体的配体,其信号通路控制细胞增殖。其他两种肽从肠道内分泌细胞分泌出来,并通过不同的机制促进营养物质的吸收。最后,第四种肽与胰高血糖素酶类似,是一种活性胰高血糖素。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
6
9366 bp
20.91
3
--
16
21

GCG Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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