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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
GCG - Glucagon
Alias:
GLP1
GLP2
GRPP
GLP-1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质实际上是一个前原蛋白,它被切割成四个不同的成熟肽。其中一种,胰高血糖素,是一种胰腺激素,通过刺激肝糖原分解和葡萄糖生成来对抗胰岛素的降低血糖作用。胰高血糖素是特异性G蛋白连接受体的配体,其信号通路控制细胞增殖。其他两种肽从肠道内分泌细胞分泌出来,并通过不同的机制促进营养物质的吸收。最后,第四种肽与胰高血糖素酶类似,是一种活性胰高血糖素。[由RefSeq,2008年7月提供]
Related ID:
NCBI:2641
ENSEMBL:ENSG00000115263
HGNC:4191
UNIPROT:P01275
OMIM:138030
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2641
1
6
9366 bp
20.91
3
--
16
21
GCG Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
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CDS(bp)
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No data available
* This data comes from NCBI.
Gene Expression
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Name
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Status
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Link
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References Literature
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